DMEI is home to the Department of Ophthalmology of the University of Oklahoma and conducts training programs for medical students, residents, and clinical fellows. The Dean McGee Eye Institute employs over 300 people in the Oklahoma City metro area. Its main facility is located in Oklahoma City on the Oklahoma Health Center campus. Satellite facilities are located in northwest Oklahoma City, Edmond, and Lawton. Subspecialists also see patients in Enid.
The first two floors of the Institute are devoted to outpatient clinics under the direction of ophthalmologists from the Department of Ophthalmology and DMEI. Patient care is provided in all the major subspecialty areas of ophthalmology including corneal and external diseases, glaucoma, medical and surgical diseases of the retina and vitreous, refractive surgery, orbital and oculoplastic diseases, neuro-ophthalmology, pediatric ophthalmology and strabismus, cataract surgery and lens implantation, ophthalmic pathology and oncology, contact lenses, ocular prosthetics, trauma and low vision services.